Ligno –Ad is a lignocaine based anaesthetic in sterile injectable form. Lignocaine stabilizes the neuronal membrane and prevents the initiation and conduction of nerve impulses, thereby effecting local anaesthetic.
Lignocaine is metabolized mainly in liver and excreted via the kidneys. Approximately 90% of lignocaine administered is excreted in the form of various metabolites, while less than 10% is excreted unchanged.
The presence of adrenalin, a vasoconstrictor, in the formulation prolongs the action of the anaesthetic localizing later to the site of injection. Therefore, the rate at which the anarsthetic passes into the bloodstream is reduced. In addition, the vasoconstrictor reduces haemorrhaging
during surgical procedures in the vicinity of the injection, thus, facilitating clinical care.
1:2,00,000
Each ml contains:
Lignocaine
Hydrochloride I.P. 21.3 mg
Adrenaline Bitrate I.P. 0.005 mg
(as Adrenaline bitrate IP o.oo9mg.)
Adrenaline 0.0125 mg
Methyl Paraben I.P. 1.0 mg
(As preservative)
Water for injection I.P. Q.S.
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